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"More than just boots! The eugenic and commercial concerns behind A. R. Kaufman's birth controlling activities".
"More than just boots! The eugenic and commercial concerns behind A. R. Kaufman's birth controlling activities".
A. R. Kaufman (1885-1979), founder of the Kitchener-based Kaufman Rubber Company, was nicknamed "Canada's Mr. Birth Control" because he established the Parents' Information Bureau (PIB)-a birth control information centre that functioned out of his factory office. Besides creating mail order/home visiting services, Kaufman also funded birth control clinics. Because he was a rubber manufacturer, it was widely believed that commercial concerns were behind his activities. This article examines recently archived material, local newspaper accounts, and court transcripts to connect A. R. Kaufman and the PIB with the manufacture of contraceptive products. It also outlines Kaufman's involvement with the eugenics movement, especially his dealings with medical practitioners who carried out sterilization procedures for the PIB., biography, historical article, journal article, research support, non-u.s. gov't, 2006, imported
"Swarm relaxation": Equilibrating a large ensemble of computer simulations⋆.
"Swarm relaxation": Equilibrating a large ensemble of computer simulations⋆.
It is common practice in molecular dynamics and Monte Carlo computer simulations to run multiple, separately-initialized simulations in order to improve the sampling of independent microstates. Here we examine the utility of an extreme case of this strategy, in which we run a large ensemble of M independent simulations (a "swarm"), each of which is relaxed to equilibrium. We show that if M is of order [Formula: see text], we can monitor the swarm's relaxation to equilibrium, and confirm its attainment, within [Formula: see text], where [Formula: see text] is the equilibrium relaxation time. As soon as a swarm of this size attains equilibrium, the ensemble of M final microstates from each run is sufficient for the evaluation of most equilibrium properties without further sampling. This approach dramatically reduces the wall-clock time required, compared to a single long simulation, by a factor of several hundred, at the cost of an increase in the total computational effort by a small factor. It is also well suited to modern computing systems having thousands of processors, and is a viable strategy for simulation studies that need to produce high-precision results in a minimum of wall-clock time. We present results obtained by applying this approach to several test cases., journal article, 2017 Nov 10, 2017 11 10, imported
A 12-year record of intertidal barnacle recruitment in Atlantic Canada (2005-2016): relationships with sea surface temperature and phytoplankton abundance.
A 12-year record of intertidal barnacle recruitment in Atlantic Canada (2005-2016): relationships with sea surface temperature and phytoplankton abundance.
On the Gulf of St. Lawrence coast of Nova Scotia (Canada), recruitment of the barnacle, journal article, 2016, 2016 10 25, imported
A 5-year study (2014-2018) of the relationship between coastal phytoplankton abundance and intertidal barnacle size along the Atlantic Canadian coast.
A 5-year study (2014-2018) of the relationship between coastal phytoplankton abundance and intertidal barnacle size along the Atlantic Canadian coast.
Benthic-pelagic coupling refers to the ecological relationships between benthic and pelagic environments. Studying such links is particularly useful to understand biological variation in intertidal organisms along marine coasts. Filter-feeding invertebrates are ecologically important on marine rocky shores, so they have often been used to investigate benthic-pelagic coupling. Most studies, however, have been conducted on eastern ocean boundaries. To evaluate benthic-pelagic coupling on a western ocean boundary, we conducted a 5-year study spanning 415 km of the Atlantic coast of Nova Scotia (Canada). We hypothesized that the summer size of intertidal barnacles (, journal article, 2019, 2019 05 02, imported
A Biomphalaria glabrata peptide that stimulates significant behaviour modifications in aquatic free-living Schistosoma mansoni miracidia.
A Biomphalaria glabrata peptide that stimulates significant behaviour modifications in aquatic free-living Schistosoma mansoni miracidia.
The human disease schistosomiasis (or bilharzia) is caused by the helminth blood fluke parasite Schistosoma mansoni, which requires an intermediate host, the freshwater gastropod snail Biomphalaria glabrata (the most common intermediate host). The free-swimming parasite miracidia utilise an excellent chemosensory sense to detect and locate an appropriate host. This study investigated the biomolecules released by the snail that stimulate changes in the behaviour of the aquatic S. mansoni miracidia. To achieve this, we have performed an integrated analysis of the snail-conditioned water, through chromatography and bioassay-guided behaviour observations, followed by mass spectrometry. A single fraction containing multiple putative peptides could stimulate extreme swimming behaviour modifications (e.g. velocity, angular variation) similar to those observed in response to crude snail mucus. One peptide (P12;-R-DITSGLDPEVADD-KR-) could replicate the stimulation of miracidia behaviour changes. P12 is derived from a larger precursor protein with a signal peptide and multiple dibasic cleavage sites, which is synthesised in various tissues of the snail, including the central nervous system and foot. P12 consists of an alpha helix secondary structure as indicated by circular dichroism spectroscopy. This information will be helpful for the development of approaches to manipulate this parasites life cycle, and opens up new avenues for exploring other parasitic diseases which have an aquatic phase using methods detailed in this investigation., journal article, research support, non-u.s. gov't, 2019 01, 2019 01 22, imported
A Characterization of Movement Skills in Obese Children With and Without Prader-Willi Syndrome.
A Characterization of Movement Skills in Obese Children With and Without Prader-Willi Syndrome.
The aim of this study was twofold: (a) to measure and compare motor proficiency in obese children with Prader-Willi syndrome (OB-PWS) to that in obese children without PWS (OB), and (b) to compare motor proficiency in OB-PWS and OB to normative data., Motor proficiency was measured using the Bruininks-Oseretsky Test of Motor Proficiency-Second Edition-Complete Form, a norm-referenced assessment of motor function. Participants were 18 OB-PWS and 44 OB (8 to 11 years of age). The scores on the 8 subtests and the total motor composite were used to compare OB-PWS and OB. Furthermore, the scores on the 4 motor-area composites were used to compare OB-PWS and OB against normative data., OB-PWS scored significantly lower than OB across all 8 subtests. OB-PWS also had significantly lower motor proficiency scores on all motor-area composites when compared with the normative sample. OB-PWS most frequently (67%-83%) scored well below average on the gross motor subtests. Although not as high as on the gross motor subtests, this finding also held true for the fine motor subtests with 39% to 45% of OB-PWS scoring well below average., Motor proficiency is very poor in OB-PWS, in particular for gross motor skills. Physical, neurological, and developmental characteristics inherent to the syndrome may explain this low performance., journal article, 2016 Sep, 2016 05 31, imported
A Loose Parts Randomized Controlled Trial to Promote Active Outdoor Play in Preschool-aged Children: Physical Literacy in the Early Years (PLEY) Project.
A Loose Parts Randomized Controlled Trial to Promote Active Outdoor Play in Preschool-aged Children: Physical Literacy in the Early Years (PLEY) Project.
The Physical Literacy in the Early Years (PLEY) intervention is a randomized mixed-methods controlled trial focused on embedding loose parts materials into the outdoor play spaces of regulated child care centres across Nova Scotia. The aim is to evaluate the efficacy of the PLEY intervention versus standard regulated childcare practice in influencing thoughts and behaviors of children, parents, and educators., Participating early child care centres (n = 19) were randomly assigned to intervention or control sites. Intervention sites received loose parts kits at the beginning of the project while control sites received kits upon project completion. The kits included items such as rocks, tree cookies, balls, wood planks, tubes, tires, ropes, and pulleys. Children (n = 183 at baseline) had their physical activity (accelerometers) and movement skills (TGMD-3 and PGMQ) measured before and after the intervention. All centres provided responses to environmental surveys (Go NAP SACC and Site Context Questionnaire), and educators in intervention sites participated in focus group and photovoice sessions. Educators were also provided with a full day professional development opportunity (plus ongoing mentoring) focused on physical activity, physical literacy, outdoor play, risk-taking, and loose parts. Parents participated in an interview addressing active outdoor play, physical literacy, and attitudes towards risk taking during play., This study will provide a better understanding of how integrating loose parts materials into outdoor play spaces impacts children's health, and the impact on educator and parent attitudes, beliefs, and understanding around physical literacy, active outdoor play and risk-taking during play., journal article, 2019 Apr 04, 2019 04 04, imported
A Sorting Statistic with Application in Neurological Magnetic Resonance Imaging of Autism.
A Sorting Statistic with Application in Neurological Magnetic Resonance Imaging of Autism.
Effect size refers to the assessment of the extent of differences between two groups of samples on a single measurement. Assessing effect size in medical research is typically accomplished with Cohen's, journal article, research support, non-u.s. gov't, research support, n.i.h., extramural, 2018, 2018 03 29, imported

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