Fiest, K M (author), Fisk, J D (author), Patten, S B (author), Tremlett, H (author), Wolfson, C (author), Warren, S (author), McKay, K A (author), Berrigan, L (author), Marrie, R A (author), CIHR Team in the Epidemiology and Impact of Comorbidity on Multiple Sclerosis (ECoMS) (author), CIBG101829 (funder), MOP-190898 (funder), MOP-93646 (funder)
Comorbidities are common in multiple sclerosis (MS). The high prevalence of pain in MS is well-established but the influence of comorbidities on pain, specifically, pain-related interference in... To examine the relationship between comorbidity and pain in MS. We recruited 949 consecutive patients with definite MS from four Canadian centres. Participants completed the Health Utilities Index (HUI-Mark III) and a validated comorbidity questionnaire at 3... The incidence of disruptive pain over two years was 31.1 per 100 persons. Fibromyalgia, rheumatoid arthritis, irritable bowel syndrome, migraine, chronic lung disease, depression, anxiety,... Comorbidity is associated with pain in persons with MS. Closer examination of these associations may provide guidance for better management of this disabling symptom in MS.